However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Take the missed dose as soon as you remember it. Avoid drinking large amounts of grapefruit juice while taking buspirone. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. It may take several weeks before you reach a dose that works for you. Buspirone comes Buspirone effects as a tablet to take by mouth.
What side effects may I notice from receiving this medication?
However, taking a higher dose of buspirone will expose your body to more of the drug. Buspirone oral tablet may cause several side effects. The list below may not include all possible serious side effects of the drug. Buspirone oral tablet may cause serious side effects. This list doesn’t include all possible mild side effects of the drug. Buspirone oral tablet can cause certain side effects, some of which are more common than others.
Buspirone: FAQ about side effects
Thus, the 5 mg tablet can also provide 2.5 mg dose, and the 10 mg tablet can provide a 5 mg dose. Chemically, buspirone hydrochloride is 8-4-4-(2-pyrimidinyl)-1-piperazinylbutyl-8-azaspiro4.5decane-7,9- dione monohydrochloride. Common drug interactions of Buspar include monoamine oxidase (MAO) inhibitors (for example, isocarboxazid Marplan), trazodone (Desyrel), warfarin (Coumadin), erythromycin, itraconazole (Sporanox), nefazodone (Serzone) and rifampin.
It is not known exactly how buspirone works to relieve the symptoms of anxiety. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first. Buspirone is a prescription medication used to treat the symptoms of Anxiety Disorders. A range of adverse effects is possible when taking BuSpar—especially within the first few weeks of taking the drug. For these reasons, it is important that your prescribing doctor is aware of all medications that you are taking before being prescribed BuSpar.
Recommended dosages
Don’t use this drug in children younger than 18 years. As a result, a higher amount of a drug stays in your body for a longer time. You may need to decide whether to stop breastfeeding or stop taking this medication. Therefore, this drug should only be used in pregnancy if clearly needed.
Food interactions warning
It is recommended that buspirone hydrochloride tablets not be used concomitantly with MAO inhibitors (see WARNINGS). The effectiveness of buspirone hydrochloride tablets in long-term use, that is, for more than 3 to 4weeks, has not been demonstrated in controlled trials. Buspirone hydrochloride tablets, USP are an antianxiety agent that is not chemically or pharmacologically related to the benzodiazepines, barbiturates, or other sedative/anxiolytic drugs. As with most drugs, buspirone oral tablet can cause an allergic reaction in some people.
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
- This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements.
- This dose can also be increased by 5 mg every 2 to 3 days if needed.
- Buspirone is available as Buspar, Bucapsol, and generic buspirone in the following dosage forms that are taken by mouth.
- If you have headaches that are bothersome with buspirone, talk with your doctor.
These symptoms could be life threatening and require immediate medical care. Call 911 if your symptoms feel life threatening or if you think you’re having a medical emergency. To learn about other mild side effects, talk with your doctor or pharmacist, or read buspirone’s prescribing information. Here’s a list of some of the mild side effects that buspirone can cause. These lists don’t include all possible side effects.
But if you have severe symptoms, immediately call 911 or your local emergency number. Call your doctor if you think you’ve taken too much buspirone. This is because food can affect how your body processes buspirone. This means that if you take buspirone with food, you should always take it with food. Ultimately, your doctor will prescribe the lowest dosage that provides the desired effect. You’ll likely take this as one 7.5 mg tablet, twice per day.
Buspirone: More common side effects
These side effects may be temporary, lasting a few days to weeks. It also comes as an oral capsule, but this article doesn’t cover that form. If you are trying to access this site from the United States, please try heading to our homepage or our drug directory. You should always consult your doctor or another healthcare professional before taking any medication. Talk with your doctor about other drug options that may work for you. Whether you have health insurance or not, cost may be a factor when you’re considering buspirone.
In vitro preclinical studies have shownthat buspirone has a high affinity for serotonin (5-HT1A) receptors. There were no effects of age on the pharmacokinetics of buspirone (see CLINICAL PHARMACOLOGY, Special Populations). The safety and effectiveness of buspirone were evaluated in two placebo-controlled 6 week trialsinvolving a total of 559 pediatric patients (ranging from 6 to 17 years of age) with GAD. The effect of buspirone hydrochloride on labor and delivery in women is unknown. No fertility impairment or fetal damage was observed in reproduction studies performed in rats andrabbits at buspirone doses of approximately 30 times the maximum recommended human dose. Chromosomal aberrations or abnormalities didnot occur in bone marrow cells of mice given one or five daily doses of buspirone.
International Patients
Some items may interact with your medicine. If it is almost time for your next dose, take only that dose. If you miss a dose, take it as soon as you can. Do not share this medicine with others. Talk to your care team about the use of this medication in children.
Information For Patients
Specifically, it is a serotonin receptor agonist, which means that it increases action at serotonin receptors in your brain. It is most often prescribed for generalized anxiety disorder. BuSpar is often less effective for disorders that involve episodes of severe anxiety, such as obsessive-compulsive disorder (OCD) and panic disorder.
- There were no effects of age on the pharmacokinetics of buspirone (see CLINICAL PHARMACOLOGY, Special Populations).
- Buspirone is a prescription medication used to treat the symptoms of Anxiety Disorders.
- There is one report suggesting that the concomitant use of Desyrel®# (trazodone hydrochloride) and buspirone may have caused 3- to 6-fold elevations on SGPT (ALT) in a few patients.
- Mild side effects of many drugs may go away within a few days to a couple of weeks.
- Do not suddenly stop taking other medicines you may take for anxiety without talking with your healthcare provider.
Buspirone is a medication that treats anxiety. Call your doctor for medical advice about side effects. Other side effects not listed may also occur in some patients.
In general, symptoms of allergic reaction can be mild or serious. But it’s not clear whether this side effect occurred in the drug’s studies. Call your doctor right away if you have serious side effects. They can also suggest ways to help reduce side effects. This decrease is thought to affect anxiety.
Do not flush this medication down the toilet. Place the medication in a safe location – one that is up and away and out of their sight and reach. Keep all medication out of sight and reach of children as many containers are not child-resistant. Keep this medication in the container it came in, tightly closed, and out of reach of children. Do not take a double dose to make up for a missed one.
In human and animal studies, buspirone has shown no potential for abuse or diversion and there is no evidence that it causes tolerance, or either physical or psychological dependence. Therapeutic levels of aspirin, desipramine, diazepam, flurazepam, ibuprofen, propranolol, thioridazine, and tolbutamide had only a limited effect on the extent of binding of buspirone to plasma proteins (see CLINICAL PHARMACOLOGY). However, there has been one report of prolonged prothrombin time when buspirone was added to the regimen of a patient treated with warfarin. Slight increases in Cmax were observed for nefazodone (8%) and its metabolite HO-NEF (11%). Patients receiving buspirone should be advised to avoid drinking such large amounts of grapefruit juice.
Do not take this medication with foods or drinks that contain grapefruit. Take this medication by mouth with water. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. BUSPIRONE (byoo SPYE rone) treats anxiety. Cleveland Clinic is a non-profit academic medical center.
Taking certain drugs used to treat fungal infections with buspirone can increase the levels of buspirone in your body. Taking certain drugs used to treat depression with buspirone can increase the levels of buspirone in your body. Your doctor may change your dosage of buspirone if you’ll be taking it with one of these drugs. Buspirone oral tablet can interact with other medications, vitamins, or herbs you may be taking. You can take buspirone oral tablets with or without food. Your doctor will recommend the dosage of buspirone oral tablet that’s right for you.
